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Article

Weighted Multi-marker Genetic Risk Scores for Incident Coronary Heart Disease among Individuals of African, Latino and East-Asian Ancestry.

Scientific reports - 1 May 2018

Iribarren Carlos, Lu Meng, Jorgenson Eric, Martínez Manuel, Lluis-Ganella Carla, Subirana Isaac, Salas Eduardo, Elosua Roberto

Abstract excerpt

We examined the clinical utility of two multi-locus genetic risk scores (GRSs) previously validated in Europeans among persons of African (AFR; n = 2,089), Latino (LAT; n = 4,349) and East-Asian (EA; n = 4,804) ancestry. We used data from the GERA cohort (30-79 years old, 68 to 73% female). We utilized two GRSs with 12 and 51 SNPs, respectively, and the Framingham Risk Score (FRS) to estimate 10-year CHD risk....

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Identifiers

PMID: 29717161
DOI: 10.1038/s41598-018-25128-x
PMCID: PMC5931622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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