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Article

Genetic risk scores for cardiometabolic traits in sub-Saharan African populations.

International journal of epidemiology - 30 Aug 2021

Ekoru Kenneth, Adeyemo Adebowale A, Chen Guanjie, Doumatey Ayo P, Zhou Jie, Bentley Amy R, Shriner Daniel, Rotimi Charles N

Abstract excerpt

BACKGROUND: There is growing support for the use of genetic risk scores (GRS) in routine clinical settings. Due to the limited diversity of current genomic discovery samples, there are concerns that the predictive power of GRS will be limited in non-European ancestry populations. GRS for cardiometabolic traits were evaluated in sub-Saharan Africans in comparison with African Americans and European Americans....

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Share to Africa South of the Sahara
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33729508
DOI: 10.1093/ije/dyab046
PMCID: PMC8407873

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