Article
The MBL2 genotype relates to COVID-19 severity and may help to select the optimal therapy.
Clinical chemistry and laboratory medicine - 27 Nov 2023
Scialò Filippo, Cernera Gustavo, Esposito Speranza, Pinchera Biagio, Gentile Ivan, Di Domenico Marina, Bianco Andrea, Pastore Lucio, Amato Felice, Castaldo Giuseppe
Abstract excerpt
OBJECTIVES: Sars-CoV-2 acute infection is clinically heterogeneous, ranging from asymptomatic cases to patients with a severe, systemic clinical course. Among the involved factors age and preexisting morbidities play a major role; genetic host susceptibility contributes to modulating the clinical expression and outcome of the disease. Mannose-binding lectin is an acute-phase protein that activates the...
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