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The MBL2 genotype relates to COVID-19 severity and may help to select the optimal therapy.

Clinical chemistry and laboratory medicine - 27 Nov 2023

Scialò Filippo, Cernera Gustavo, Esposito Speranza, Pinchera Biagio, Gentile Ivan, Di Domenico Marina, Bianco Andrea, Pastore Lucio, Amato Felice, Castaldo Giuseppe

Abstract excerpt

OBJECTIVES: Sars-CoV-2 acute infection is clinically heterogeneous, ranging from asymptomatic cases to patients with a severe, systemic clinical course. Among the involved factors age and preexisting morbidities play a major role; genetic host susceptibility contributes to modulating the clinical expression and outcome of the disease. Mannose-binding lectin is an acute-phase protein that activates the...

Topics

Humans
COVID-19
SARS-CoV-2
Genotype
Genetic Predisposition to Disease
Mannose-Binding Lectin
Inflammation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37313996
DOI: 10.1515/cclm-2023-0183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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