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Article

A dual role for Mannan-binding lectin-associated serine protease 2 (MASP-2) in HIV infection.

Molecular immunology - 1 Oct 2016

Boldt Angelica Beate Winter, Beltrame Márcia Holsbach, Catarino Sandra Jeremias, Meissner Caroline Grisbach, Tizzot Regina, Messias-Reason Iara Jose

Abstract excerpt

BACKGROUND: Mannan-binding lectin (MBL) - associated serine protease 2 (MASP-2) co-activates the lectin pathway of complement in response to several viral infections. The quality of this response partly depends on MASP2 gene polymorphisms, which modulate MASP-2 function and serum levels. In this study we investigated a possible role of MASP2 polymorphisms, MASP-2 serum levels and MBL-mediated complement...

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Source

Identifiers

PMID: 27588826
DOI: 10.1016/j.molimm.2016.08.015

Genes

MASP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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