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Article

TGF-β Polymorphisms Are a Risk Factor for Chagas Disease.

Disease markers - 1 Jan 2018

Ferreira Roberto Rodrigues, Madeira Fabiana da Silva, Alves Gabriel Farias, Chambela Mayara da Costa, Curvo Eduardo de Oliveira Vaz, Moreira Aline Dos Santos, Almeida de Sá Renata, Mendonça-Lima Leila, Cabello Pedro Hernan, Bailly Sabine, Feige Jean-Jacques, Araujo-Jorge Tania Cremonini, Saraiva Roberto Magalhães, Waghabi Mariana Caldas

Abstract excerpt

Transforming growth factor β1 (TGF-β1) is an important mediator in Chagas disease. Furthermore, patients with higher TGF-β1 serum levels show a worse clinical outcome. Gene polymorphism may account for differences in cytokine production during infectious diseases. We tested whether TGFB1 polymorphisms could be associated with Chagas disease susceptibility and severity in a Brazilian population. We investigated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29670670
DOI: 10.1155/2018/4579198
PMCID: PMC5835243

Genes

TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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