Article
TGF-beta1 and IL-6 gene polymorphism in Spanish brucellosis patients.
Cytokine - 1 Oct 2008
Bravo María José, Colmenero Juan Dios, Queipo-Ortuño María Isabel, Alonso Antonio, Caballero Abelardo
Abstract excerpt
Polymorphisms in the cytokine genes have allowed for the understanding of the genetic determinants in several diseases. We investigated the polymorphism of the transforming growth factor (TGF)-beta1 and IL-6 genes in relation to susceptibility to human brucellosis. We typed 82 Spanish brucellosis patients and 102 healthy controls for TGF-beta1 polymorphisms in codons 10 and 25, and IL-6 promoter polymorphism at...
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