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Article

Analyses of the yeast Rad51 recombinase A265V mutant reveal different in vivo roles of Swi2-like factors.

Nucleic acids research - 1 Aug 2011

Chi Peter, Kwon YoungHo, Visnapuu Mari-Liis, Lam Isabel, Santa Maria Sergio R, Zheng Xiuzhong, Epshtein Anastasiya, Greene Eric C, Sung Patrick, Klein Hannah L

Abstract excerpt

The Saccharomyces cerevisiae Swi2-like factors Rad54 and Rdh54 play multifaceted roles in homologous recombination via their DNA translocase activity. Aside from promoting Rad51-mediated DNA strand invasion of a partner chromatid, Rad54 and Rdh54 can remove Rad51 from duplex DNA for intracellular recycling. Although the in vitro properties of the two proteins are similar, differences between the phenotypes of the...

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Identifiers

PMID: 21558173
DOI: 10.1093/nar/gkr297
PMCID: PMC3159464

Genes

RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analyses of the yeast Rad51 recombinase A265V mutant reveal different in vivo roles of Swi2-like factors.PMID 21558173Read ↗

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Synergistic action of the Saccharomyces cerevisiae homologous recombination factors Rad54 and Rad51 in chromatin remodeling.Semantic proximity Read ↗

Potential Rad54 separation of function mutation highlights unique roles during homologous recombination.Semantic proximity Read ↗

Novel insights into RAD51 activity and regulation during homologous recombination and DNA replicationSemantic proximity Read ↗

A new Saccharomyces cerevisiae strain with a mutant Smt3-deconjugating Ulp1 protein is affected in DNA replication and requires Srs2 and homologous recombination for its viability.Semantic proximity Read ↗

Rad51 paralog complex Rad55–Rad57 acts as a molecular chaperone during homologous recombinationSemantic proximity Read ↗

The translocation activity of Rad54 reduces crossover outcomes during homologous recombinationSemantic proximity Read ↗

Genome instability in rad54 mutants of Saccharomyces cerevisiae.Semantic proximity Read ↗

Mechanistic insights into RAD51-associated protein 1 (RAD51AP1) action in homologous DNA repair.Semantic proximity Read ↗

Swc2 is a widely conserved H2AZ-binding module essential for ATP-dependent histone exchange.Semantic proximity Read ↗

The translocation activity of Rad54 reduces crossover outcomes during homologous recombination.Semantic proximity Read ↗

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