Article

Rad9/53BP1 promotes crossover recombination DNA repair by limiting the Sgs1 and Mph1 helicases

2019-05-15

Abstract excerpt

A DNA double strand break (DSB) is primed for homologous recombination (HR) repair through the nucleolytic processing (resection) of its ends, leading to the formation of a 3′ single-stranded DNA (ssDNA). Generation of the ssDNA is accompanied by the loading of several repair factors, including the ssDNA binding factor RPA and the recombinase Rad51. Then, depending upon the availability and location of a homologou...

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Literature Corpus work: 7dd12a29-2108-5650-9fff-f74211804df0
DOI: 10.1101/638791

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