Article
Copy number of pancreatic polypeptide receptor gene NPY4R correlates with body mass index and waist circumference.
PloS one - 1 Jan 2018
Shebanits Kateryna, Andersson-Assarsson Johanna C, Larsson Ingrid, Carlsson Lena M S, Feuk Lars, Larhammar Dan
Abstract excerpt
Multiple genetic studies have linked copy number variation (CNV) in different genes to body mass index (BMI) and obesity. A CNV on chromosome 10q11.22 has been associated with body weight. This CNV region spans NPY4R, the gene encoding the pancreatic polypeptide receptor Y4, which has been described as a satiety-stimulating receptor. We have investigated CNV of the NPY4R gene and analysed its relationship to BMI,...
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