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Article

Copy Number Variations in Candidate Genes and Intergenic Regions Affect Body Mass Index and Abdominal Obesity in Mexican Children.

BioMed research international - 1 Jan 2017

Antúnez-Ortiz Diana Lizzete, Flores-Alfaro Eugenia, Burguete-García Ana Isabel, Bonnefond Amélie, Peralta-Romero Jesús, Froguel Philippe, Espinoza-Rojo Mónica, Cruz Miguel

Abstract excerpt

Introduction. Increase in body weight is a gradual process that usually begins in childhood and in adolescence as a result of multiple interactions among environmental and genetic factors. This study aimed to analyze the relationship between copy number variants (CNVs) in five genes and four intergenic regions with obesity in Mexican children. Methods. We studied 1423 children aged 6-12 years. Anthropometric...

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Topics

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Share to Body Composition
Share to Cell Adhesion Molecules, Neuronal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Intergenic

Share to GPI-Linked Proteins

Share to Obesity, Abdominal

Share to Receptors, Leptin

Share to Rho Guanine Nucleotide Exchange Factors

Share to Waist Circumference

Source

Open in PubMed Open full text

Identifiers

PMID: 28428959
DOI: 10.1155/2017/2432957
PMCID: PMC5385910

Genes

ARHGEF4
CPXCR1
LEPR
NEGR1
INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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