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Article

Polymorphisms in the NPY2R gene show significant associations with BMI that are additive to FTO, MC4R, and NPFFR2 gene effects.

Obesity (Silver Spring, Md.) - 1 Nov 2011

Hunt Steven C, Hasstedt Sandra J, Xin Yuanpei, Dalley Brian K, Milash Brett A, Yakobson Emanuel, Gress Richard E, Davidson Lance E, Adams Ted D

Abstract excerpt

Neuropeptide Y (NPY) is an appetite hormone that acts centrally to control feeding behavior. The 5' and exon 2 regions of NPY2R, one of five NPY receptor genes, have been weakly and inconsistently implicated with obesity. With the ATG start site of the gene at the beginning of exon 2, single-nucleotide polymorphisms (SNPs) across intron 1 may show stronger associations with obesity than expected. Two 5' SNPs,...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Melanocortin, Type 4

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Source

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Identifiers

PMID: 21818152
DOI: 10.1038/oby.2011.239
PMCID: PMC3733173

Genes

NPFFR2
FTO
NPY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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