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Article

Candidate molecular pathway genes related to appetite regulatory neural network, adipocyte homeostasis and obesity: results from the CARDIA Study.

Annals of human genetics - 1 Sept 2010

Friedlander Yechiel, Li Guo, Fornage Myriam, Williams O Dale, Lewis Cora E, Schreiner Pamela, Pletcher Mark J, Enquobahrie Daniel, Williams Michelle, Siscovick David S

Abstract excerpt

Appetite regulatory neural network and adipocyte homeostasis molecular pathways are critical to long-term weight maintenance. Associations between obesity-related phenotypes and four genes in these pathways - leptin (LEP), leptin receptor (LEPR), neuropeptide Y2 receptor (NPY2R) and peptide YY (PYY) were examined in CARDIA Study participants (aged 18-30 at recruitment in 1985-6). Weight, BMI and waist...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20642810
DOI: 10.1111/j.1469-1809.2010.00596.x
PMCID: PMC2945878

Genes

LEP
PYY
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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