Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men.

Diabetes - 1 May 2007

Campbell Catarina D, Lyon Helen N, Nemesh James, Drake Jared A, Tuomi Tiinamaija, Gaudet Daniel, Zhu Xiaofeng, Cooper Richard S, Ardlie Kristin G, Groop Leif C, Hirschhorn Joel N

Abstract excerpt

The neuropeptide Y (NPY) family of peptides and receptors regulate food intake. Inherited variation in this pathway could influence susceptibility to obesity and its complications, including type 2 diabetes. We genotyped a set of 71 single nucleotide polymorphisms (SNPs) that capture the most common variation in NPY, PPY, PYY, NPY1R, NPY2R, and NPY5R in 2,800 individuals of recent European ancestry drawn from the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Mass Index
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ethnicity

Share to Linkage Disequilibrium

Share to Neuropeptide Y

Share to Receptors, Neuropeptide Y

Share to Reference Values

Share to Sex Characteristics

Source

Identifiers

PMID: 17325259
DOI: 10.2337/db06-1051

Genes

NPY
PPY
PYY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men.PMID 17325259Read ↗

Polymorphisms in the NPY2R gene show significant associations with BMI that are additive to FTO, MC4R, and NPFFR2 gene effects.Semantic proximity Read ↗

Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects.Semantic proximity Read ↗

Variations in peptide YY and Y2 receptor genes are associated with severe obesity in Pima Indian men.Semantic proximity Read ↗

Single nucleotide polymorphisms in the neuropeptide Y2 receptor (NPY2R) gene and association with severe obesity in French white subjects.Semantic proximity Read ↗

Studies of the peptide YY and neuropeptide Y2 receptor genes in relation to human obesity and obesity-related traits.Semantic proximity Read ↗

Novel polymorphisms in the neuropeptide-Y Y5 receptor associated with obesity in Pima Indians.Semantic proximity Read ↗

Heredity and cardiometabolic risk: naturally occurring polymorphisms in the human neuropeptide Y(2) receptor promoter disrupt multiple transcriptional response motifs.Semantic proximity Read ↗

Candidate molecular pathway genes related to appetite regulatory neural network, adipocyte homeostasis and obesity: results from the CARDIA Study.Semantic proximity Read ↗

Neuropeptide Y gene variants in obesity, dietary intake, blood pressure, lipid and glucose metabolism: A longitudinal birth cohort study.Semantic proximity Read ↗

A PYY Q62P variant linked to human obesity.Semantic proximity Read ↗

Sequence variation within the neuropeptide Y gene and obesity in Mexican Americans.Semantic proximity Read ↗

Copy number of pancreatic polypeptide receptor gene NPY4R correlates with body mass index and waist circumference.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.