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Article

CNV analysis and mutation screening indicate an important role for the NPY4R gene in human obesity.

Obesity (Silver Spring, Md.) - 1 Apr 2016

Aerts Evi, Beckers Sigri, Zegers Doreen, Van Hoorenbeeck Kim, Massa Guy, Verrijken An, Verhulst Stijn L, Van Gaal Luc F, Van Hul Wim

Abstract excerpt

OBJECTIVE: Genome-wide copy number variation (CNV) analyses have associated the 10q11.22 CNV with obesity. As the NPY4R gene is the most interesting candidate gene in this region, it was hypothesized that both genetic and structural variation in NPY4R might be implicated in the pathogenesis of obesity. METHODS: In the first part of this study, 326 children and adolescents with obesity and 298 healthy lean...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26921218
DOI: 10.1002/oby.21435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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