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Article

The Dictyostelium RasS protein is required for macropinocytosis, phagocytosis and the control of cell movement.

Journal of cell science - 1 Feb 2000

Chubb J R, Wilkins A, Thomas G M, Insall R H

Abstract excerpt

Endocytosis and cell migration both require transient localised remodelling of the cell cortex. Several lines of evidence suggest a key regulatory role in these activities for members of the Ras family of small GTPases. We have generated Dictyostelium cells lacking one member of this family, RasS, and the mutant cells are perturbed in endocytosis and cell migration. Mutant amoebae are defective in phagocytosis...

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Identifiers

PMID: 10652263
DOI: 10.1242/jcs.113.4.709

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Dictyostelium RasS protein is required for macropinocytosis, phagocytosis and the control of cell movement.PMID 10652263Read ↗

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