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HLA-A*02:07 Allele Associates with Clarithromycin-Induced Cutaneous Adverse Drug Reactions in Chinese Patients.

Basic & clinical pharmacology & toxicology - 1 Sept 2018

Chen Sheng-An, Zhang Li-Rong, Yang Fan-Ping, Yang Lin-Lin, Yang Ying, Chen Zi-Hua, Jiang Meng-Lin, Xiong Hao, Zhu Hui-Zhong, Qi Zheng, Xing Qing-He, Luo Xiao-Qun

Abstract excerpt

Genetic risk factors could cause cutaneous adverse drug reactions (cADRs) in patients after treatment with clarithromycin. This study explored the association of HLA class I genes with clarithromycin-cADRs in Han Chinese patients. A total of 12 clarithromycin-cADR patients and 34 clarithromycin-tolerant controls were recruited for the high-resolution genotyping of HLA class I genes (HLA-A, HLA-B and HLA-C). The...

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PMID: 29575644
DOI: 10.1111/bcpt.13011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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