Article
HLA-B*51:01 is strongly associated with clindamycin-related cutaneous adverse drug reactions.
The pharmacogenomics journal - 1 Dec 2017
Yang Y, Chen S, Yang F, Zhang L, Alterovitz G, Zhu H, Xuan J, Yang X, Luo H, Mu J, He L, Luo X, Xing Q
Abstract excerpt
Clindamycin causes cutaneous adverse drug reactions (cADRs), sometimes with the mechanisms of pathogenicity or risk factors unknown. This study aims to assess whether HLA alleles are associated with clindamycin-related cADRs in the Han Chinese population. We performed an association study of 12 subjects with clindamycin-related cADRs, 279 controls and 26 clindamycin-tolerant subjects. Subjects who received...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
