Article
Research on Susceptible Genes and Immunological Pathogenesis of Cutaneous Adverse Drug Reactions in Chinese Hans.
The journal of investigative dermatology. Symposium proceedings - 1 Jul 2015
Yang Fangping, Yang Ying, Zhu Qinyuan, Chen Sheng-An, Fu Xiaodan, Yan Sijia, Meng Chunjie, Ma Li, Sun Xinfen, Xu Jinhua, Luo Xiaoqun, Xing Qinghe
Abstract excerpt
Cutaneous adverse drug reactions (cADRs) include mild maculopapular exanthems (MPE), Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), drug reaction with eosinophilia and systemic symptoms (DRESS) and acute generalized exanthematous pustulosis (AGEP). We used HLA high-resolution genotyping and genome wide association analysis (GWAS) to identify the genetic markers for cADRs induced by common...
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