Article
Association between human leukocyte antigens and cutaneous adverse drug reactions to antiepileptics and antibiotics in the Iranian population.
Dermatologic therapy - 1 May 2022
Mortazavi Hossein, Rostami Anahita, Firooz Alireza, Esmaili Nafiseh, Ghiasi Maryam, Lajevardi Vahideh, Amirzargar Ali Akbar, Sheykhi Iman, Khamesipour Ali, Akhdar Marwa
Abstract excerpt
In this case-control study, class І and ІІ human leukocyte antigen (HLA) alleles in Iranian patients with benign and severe cutaneous adverse drug reactions (CADRs) due to aromatic anticonvulsants and antibiotics were evaluated. Patients diagnosed with CADRs (based on clinical and laboratory findings) with a Naranjo score of ≥ 4 underwent blood sampling and HLA-DNA typing. The control group comprised 90 healthy...
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