Article
Towards Understanding MCR-like Colistin Resistance.
Trends in microbiology - 1 Sept 2018
Sun Jian, Zhang Huimin, Liu Ya-Hong, Feng Youjun
Abstract excerpt
Antibiotic resistance has become a global public health priority. Polymyxins, a family of cationic polypeptide antibiotics, act as a final line of refuge against severe infections by Gram-negative pathogens with pan-drug resistance. Unfortunately, this last-resort antibiotic has been challenged by the emergence and global spread of mobilized colistin resistance determinants (mcr). Given the fact that it has...
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