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Analysis of mcr family of colistin resistance genes in Gram-negative isolates from a tertiary care hospital in India

1 Jul 2024

Abstract excerpt

AIM: Colistin serves as the drug of last resort for combating numerous multidrug-resistant (MDR) Gram-negative infections. Its efficacy is hampered by the prevalent issue of colistin resistance, which severely limits treatment options for critically ill patients. Identifying resistance genes is crucial for controlling resistance spread, with horizontal gene transfer being the primary mechanism among bacteria....

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PMID: 38986507
DOI: 10.1093/jambio/lxae172

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