Article
Global epidemiology, genetic environment, risk factors and therapeutic prospects of mcr genes: A current and emerging update
26 Aug 2022
Abstract excerpt
Background Mobile colistin resistance ( mcr ) genes modify Lipid A molecules of the lipopolysaccharide, changing the overall charge of the outer membrane. Results and discussion Ten mcr genes have been described to date within eleven Enterobacteriaceae species, with Escherichia coli , Klebsiella pneumoniae , and Salmonella species being the most predominant. They are present worldwide in 72 countries, with animal...
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