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Article

Colistin resistance in Gram-negative bacteria analysed by five phenotypic assays and inference of the underlying genomic mechanisms

2021-06-14

Abstract excerpt

<title>Abstract</title> <p>Background Colistin is used against multi-drug resistant pathogens, yet resistance emerges either through dissemination of plasmid-mediated genes (<italic>mcr</italic>) or chromosomal mutation of genes involved in lipopolysaccharide synthesis (i.e. <italic>mgrB, phoPQ, pmrCAB).</italic> Phenotypic susceptibility testing is challenging due to poor diffusion of colistin in agar media, le...

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Literature Corpus work
0a68818f-30a4-5911-98e5-a86e016a7110
DOI
10.21203/rs.3.rs-610993/v1
Open publication

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Colistin resistance in Gram-negative bacteria analysed by five phenotypic assays and inference of the underlying genomic mechanismsDOI 10.21203/rs.3.rs-610993/v1
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