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Article

Genetic markers of dopaminergic transmission predict performance for older males but not females.

Neurobiology of aging - 1 Jun 2018

Hupfeld Kathleen E, Vaillancourt David E, Seidler Rachael D

Abstract excerpt

Mobility and memory declines with aging can limit independence. Several single-nucleotide polymorphisms have been associated with cognitive performance, but studies investigating motor function are scant. We examined 4 single-nucleotide polymorphisms involved in dopaminergic metabolism: BDNF (Val66Met), DRD3 (Ser9Gly), DBH (C>T), and COMT (Val158Met) for their relationship to motor and cognitive function in...

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Source

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Identifiers

PMID: 29525179
DOI: 10.1016/j.neurobiolaging.2018.02.005
PMCID: PMC5924602

Genes

BDNF
COMT
DBH
DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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