Article
A common polymorphism in the dopamine transporter gene predicts working memory performance and in vivo dopamine integrity in aging.
NeuroImage - 15 Dec 2021
Karalija Nina, Köhncke Ylva, Düzel Sandra, Bertram Lars, Papenberg Goran, Demuth Ilja, Lill Christina M, Johansson Jarkko, Riklund Katrine, Lövdén Martin, Bäckman Lars, Nyberg Lars, Lindenberger Ulman, Brandmaier Andreas M
Abstract excerpt
Dopamine (DA) integrity is suggested as a potential cause of individual differences in working memory (WM) performance among older adults. Still, the principal dopaminergic mechanisms giving rise to WM differences remain unspecified. Here, 61 single-nucleotide polymorphisms, located in or adjacent to various dopamine-related genes, were assessed for their links to WM performance in a sample of 1313 adults aged...
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