Article
Impact of five SNPs in dopamine-related genes on executive function.
Acta neurologica Scandinavica - 1 Jan 2013
Mitaki S, Isomura M, Maniwa K, Yamasaki M, Nagai A, Nabika T, Yamaguchi S
Abstract excerpt
OBJECTIVES: Dopamine neurotransmission is a critical factor for executive function, which is controlled by the prefrontal cortex in humans. Although the contribution of genetic factors to the regulation of brain dopaminergic activity is widely acknowledged, identification of a genotype-phenotype association has not yet been clearly established. In this study, we therefore evaluated the effects of five functional...
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