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Article

Joint and Individual Mitochondrial DNA Variation and Cognitive Outcomes in Black and White Older Adults.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Sept 2024

Odden Michelle C, Li Yongmei, Jotwani Vasantha, Dobrota Sylvie, Tan Annabel X, Cummings Steven R, Shlipak Michael G, Scherzer Rebecca, Ix Joachim H, Buckwalter Marion S, Tranah Gregory J

Abstract excerpt

BACKGROUND: Mitochondrial dysfunction manifests in neurodegenerative diseases and other age-associated disorders. In this study, we examined variation in inherited mitochondrial DNA (mtDNA) sequences in Black and White participants from 2 large aging studies to identify variants related to cognitive function. METHODS: Participants included self-reported Black and White adults aged ≥70 years in the Lifestyle...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39007867
DOI: 10.1093/gerona/glae170
PMCID: PMC11345514

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