Article
Lipid phosphate phosphatase 3 in vascular pathophysiology.
Atherosclerosis - 1 Apr 2018
Busnelli Marco, Manzini Stefano, Parolini Cinzia, Escalante-Alcalde Diana, Chiesa Giulia
Abstract excerpt
LPP3 is an integral membrane protein belonging to a family of enzymes (LPPs) that display broad substrate specificity and catalyse dephosphorylation of several lipid substrates, including lysophosphatidic acid and sphingosine-1-phosphate. In mammals, the LPP family consists of three enzymes named LPP1, LPP2 and LPP3, which are encoded by three independent genes, PLPP1, PLPP2 and PLPP3, respectively (formerly...
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