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Article

Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2014

Smyth Susan S, Mueller Paul, Yang Fanmuyi, Brandon J Anthony, Morris Andrew J

Abstract excerpt

The structurally simple glycero- and sphingo-phospholipids, lysophosphatidic acid (LPA) and sphingosine-1-phosphate, serve as important receptor-active mediators that influence blood and vascular cell function and are positioned to influence the events that contribute to the progression and complications of atherosclerosis. Growing evidence from preclinical animal models has implicated LPA, LPA receptors, and key...

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Source

Open in PubMed Open full text

Identifiers

PMID: 24482375
DOI: 10.1161/ATVBAHA.113.302737
PMCID: PMC3944085

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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