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Article

Generation of a conditional Ppap2b/Lpp3 null allele.

Genesis (New York, N.Y. : 2000) - 1 Jul 2007

Escalante-Alcalde Diana, Sánchez-Sánchez Roberto, Stewart Colin L

Abstract excerpt

Lpp3, formerly known as Pap2b, is a lipid phosphohydrolase enzyme. Some of its substrates and products are lipids with potent biological and signaling activities such as phosphatidic acid, lysophosphatidic acid, sphingosine-1-phosphate, diacylglycerol, sphingosine, and ceramide. Lpp3 is dynamically expressed during development and is widely distributed in adult tissues. Targeted inactivation of Lpp3 gene (Ppap2b)...

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Identifiers

PMID: 17610274
DOI: 10.1002/dvg.20314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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