Article
Notch3 in Development, Health and Disease.
Biomolecules - 23 Mar 2020
Hosseini-Alghaderi Samira, Baron Martin
Abstract excerpt
Notch3 is one of four mammalian Notch proteins, which act as signalling receptors to control cell fate in many developmental and adult tissue contexts. Notch signalling continues to be important in the adult organism for tissue maintenance and renewal and mis-regulation of Notch is involved in many diseases. Genetic studies have shown that Notch3 gene knockouts are viable and have limited developmental defects,...
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