Article
Measurements of auto-antibodies to α-synuclein in the serum and cerebral spinal fluids of patients with Parkinson's disease.
Journal of neurochemistry - 1 Jun 2018
Akhtar Rizwan S, Licata Joseph P, Luk Kelvin C, Shaw Leslie M, Trojanowski John Q, Lee Virginia M-Y
Abstract excerpt
Biomarkers for α-synuclein are needed for diagnosis and prognosis in Parkinson's disease (PD). Endogenous auto-antibodies to α-synuclein could serve as biomarkers for underlying synucleinopathy, but previous assessments of auto-antibodies have shown variability and inconsistent clinical correlations. We hypothesized that auto-antibodies to α-synuclein could be diagnostic for PD and explain its clinical...
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