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Article

Αlpha-synuclein levels in blood plasma from LRRK2 mutation carriers.

PloS one - 1 Jan 2012

Gorostidi Ana, Bergareche Alberto, Ruiz-Martínez Javier, Martí-Massó José F, Cruz María, Varghese Shiji, Qureshi Mohamed M, Alzahmi Fatimah, Al-Hayani Abdulmonem, López de Munáin Adolfo, El-Agnaf Omar M A

Abstract excerpt

The diagnosis of Parkinson's disease (PD) remains primarily a clinical issue, based mainly on phenotypic patterns. The identification of biomarkers capable of permitting the preclinical detection of PD is critically needed. α-Synuclein is a key protein in PD, with missense and multiplication mutations in the gene encoding α-synuclein (SNCA) having been reported in familial cases of PD, and accumulation of the...

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Identifiers

PMID: 23300640
DOI: 10.1371/journal.pone.0052312
PMCID: PMC3531490

Genes

SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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