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Article

Aggregated α-synuclein in erythrocytes as a potential biomarker for idiopathic Parkinson's Disease

6 Feb 2025

Abstract excerpt

BACKGROUND: Mostly known for its implication in synucleinopathies, including Parkinson's disease (PD), α-synuclein is predominantly expressed in the nervous system. Most of the peripheral α-synuclein is found in erythrocytes, and several studies have examined a possible association between erythrocytic α-synuclein and PD. METHODS: We have used a recently developed ELISA that selectively detects fibrillar and...

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PMID: 39938327
DOI: 10.1016/j.parkreldis.2025.107321

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