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Article

Computational engineering of cellulase Cel9A-68 functional motions through mutations in its linker region.

Physical chemistry chemical physics : PCCP - 14 Mar 2018

Costa M G S, Silva Y F, Batista P R

Abstract excerpt

Microbial cellulosic degradation by cellulases has become a complementary approach for biofuel production. However, its efficiency is hindered by the recalcitrance of cellulose fibres. In this context, computational protein design methods may offer an efficient way to obtain variants with improved enzymatic activity. Cel9A-68 is a cellulase from Thermobifida fusca that is still active at high temperatures. In a...

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PMID: 29497721
DOI: 10.1039/c7cp07073j

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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