Article
Novel approach for CES1 genotyping: integrating single nucleotide variants and structural variation.
Pharmacogenomics - 1 Mar 2018
Bjerre Ditte, Berg Rasmussen Henrik, Indices Consortium The
Abstract excerpt
AIM: Development of a specific procedure for genotyping of CES1A1 (CES1) and CES1A2, a hybrid of CES1A1 and the pseudogene CES1P1. MATERIALS & METHODS: The number of CES1A1 and CES1A2 copies and that of CES1P1 were determined using real-time PCR. Long range PCRs followed by secondary PCRs allowed sequencing of single nucleotide variants in CES1A1 and CES1A2. RESULTS & CONCLUSION: A procedure consisting of two...
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