Analysis of hepatitis B virus preS1 variability and prevalence of the rs2296651 polymorphism in a Spanish population.

doi:10.3748/wjg.v24.i6.680

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Article

Analysis of hepatitis B virus preS1 variability and prevalence of the rs2296651 polymorphism in a Spanish population.

World journal of gastroenterology - 14 Feb 2018

Casillas Rosario, Tabernero David, Gregori Josep, Belmonte Irene, Cortese Maria Francesca, González Carolina, Riveiro-Barciela Mar, López Rosa Maria, Quer Josep, Esteban Rafael, Buti Maria, Rodríguez-Frías Francisco

Abstract excerpt

AIM: To determine the variability/conservation of the domain of hepatitis B virus (HBV) preS1 region that interacts with sodium-taurocholate cotransporting polypeptide (hereafter, NTCP-interacting domain) and the prevalence of the rs2296651 polymorphism (S267F, NTCP variant) in a Spanish population. METHODS: Serum samples from 246 individuals were included and divided into 3 groups: patients with chronic HBV...

Topics

Adult
Aged
DNA, Viral
Female
Genotype
Hepatitis B Surface Antigens
Hepatitis B virus
Hepatitis B, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

High-Throughput Nucleotide Sequencing

Humans

Male

Middle Aged

Organic Anion Transporters, Sodium-Dependent

Polymorphism, Single Nucleotide

Protein Precursors

Sequence Analysis, DNA

Spain

Symporters

Source

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Identifiers

PMID: 29456407
DOI: 10.3748/wjg.v24.i6.680
PMCID: PMC5807671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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