Article
NTCP gene polymorphisms and hepatitis B virus infection status in a Ghanaian population.
Virology journal - 3 Jul 2020
Nyarko Eric, Obirikorang Christian, Owiredu W K B A, Adu Evans Asamoah, Acheampong Emmanuel, Aidoo Freeman, Ofori Emmanuel, Addy Bright Selorm, Asare-Anane Henry
Abstract excerpt
BACKGROUND: SLC10A1 gene codes NTCP, a receptor through which the hepatitis B virus (HBV) gets access into hepatocytes - a stage of the viral cycle necessary for replication. Polymorphism variants of SLC10A1 play roles in HBV infection, viral clearance, treatment outcome, and complications, in diverse ethnic groups and countries. However, no such study has been conducted in the Ghanaian population, a country with...
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