The p.Ser267Phe variant in SLC10A1 is associated with resistance to chronic hepatitis B

doi:10.1002/hep.27608

Article

The p.Ser267Phe variant in SLC10A1 is associated with resistance to chronic hepatitis B

21 Nov 2014

Abstract excerpt

UNLABELLED: In the past 50 years there have been considerable efforts to identify the cellular receptor of hepatitis B virus (HBV). Recently, in vitro evidence from several groups has shown that the sodium-taurocholate cotransporting polypeptide (NTCP, which is encoded by SLC10A1 and transports bile acids into hepatic cells in enterohepatic recirculation) is a strong candidate. In particular, in vitro the...

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