Article
A genetic variant of the NTCP gene is associated with HBV infection status in a Chinese population.
BMC cancer - 12 Mar 2016
Yang Jingmin, Yang Yuan, Xia Mingying, Wang Lianghui, Zhou Weiping, Yang Yajun, Jiang Yueming, Wang Hongyang, Qian Ji, Jin Li, Wang Xiaofeng
Abstract excerpt
BACKGROUND: To investigate whether genetic variants of the HBV receptor gene NTCP are associated with HBV infection in the Han Chinese population. METHODS: We sequenced the entire 23 kb NTCP gene from 111 HBeAg-positive HBsAg carriers (PSE group), 110 HBeAg-negative HBsAg carriers (PS group), and 110 control subjects. Then, we performed association analyses of suggestively significant SNPs with HBV infection in...
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