Article
Whole-genome sequencing reveals the mechanisms for evolution of streptomycin resistance in Lactobacillus plantarum.
Journal of dairy science - 1 Apr 2018
Zhang Fuxin, Gao Jiayuan, Wang Bini, Huo Dongxue, Wang Zhaoxia, Zhang Jiachao, Shao Yuyu
Abstract excerpt
In this research, we investigated the evolution of streptomycin resistance in Lactobacillus plantarum ATCC14917, which was passaged in medium containing a gradually increasing concentration of streptomycin. After 25 d, the minimum inhibitory concentration (MIC) of L. plantarum ATCC14917 had reached 131,072 µg/mL, which was 8,192-fold higher than the MIC of the original parent isolate. The highly resistant L....
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