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Gain and Loss of Acquired Doxycycline Resistance in <i>Lactiplantibacillus plantarum</i> : An Adaptive Laboratory Evolution Study

2026-03-18

Abstract excerpt

Probiotics interact in a mutualistic way with humans. Exposure of probiotics to sublethal concentrations of commonly prescribed antibiotics can cause resistance to arise. Over 1000 generations, we performed an adaptive laboratory evolution (ALE) experiment to determine if the fitness of the probiotic Lactobacillus plantarum is altered by exposure to doxycycline (DOX) at 1/10 MIC. Compared to the original culture,...

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Literature Corpus work
f7dda6e2-8702-54fa-9763-22c838355084
DOI
10.64898/2026.03.17.712413
Open publication

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Gain and Loss of Acquired Doxycycline Resistance in <i>Lactiplantibacillus plantarum</i> : An Adaptive Laboratory Evolution StudyDOI 10.64898/2026.03.17.712413
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