Article
The contribution of a novel ribosomal S12 mutation to aminoglycoside resistance of Escherichia coli mutants.
Journal of chemotherapy (Florence, Italy) - 1 Aug 2004
Gill A E, Amyes S G B
Abstract excerpt
This study characterised the contribution of a novel ribosomal S12 mutation to aminoglycoside resistance in Escherichia coli via step-wise mutation analysis. Mutants of E. coli NCTC 10418 were selected in four separate progressive series (I-IV) on plates containing increasing aminoglycoside (streptomycin, neomycin, gentamicin, tobramycin, and kanamycin) concentrations. Minimum inhibitory concentrations (MICs) of...
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