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Article

Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni.

Antimicrobial agents and chemotherapy - 1 Mar 2013

Hao Haihong, Yuan Zonghui, Shen Zhangqi, Han Jing, Sahin Orhan, Liu Peng, Zhang Qijing

Abstract excerpt

Macrolide antibiotics are important for clinical treatment of infections caused by Campylobacter jejuni. Development of resistance to this class of antibiotics in Campylobacter is a complex process, and the dynamic molecular changes involved in this process remain poorly defined. Multiple lineages of macrolide-resistant mutants were selected by stepwise exposure of C. jejuni to escalating doses of erythromycin or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23274667
DOI: 10.1128/AAC.01927-12
PMCID: PMC3591901

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