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Article

Genome adaptive evolution of Lactobacillus casei under long-term antibiotic selection pressures.

BMC genomics - 24 Apr 2017

Wang Jicheng, Dong Xiao, Shao Yuyu, Guo Huiling, Pan Lin, Hui Wenyan, Kwok Lai-Yu, Zhang Heping, Zhang Wenyi

Abstract excerpt

BACKGROUND: The extensive use of antibiotics in medicine has raised serious concerns about biosafety. However, the effect of antibiotic application on the adaptive evolution of microorganisms, especially to probiotic bacteria, has not been well characterized. Thus, the objective of the current work was to investigate how antibiotic selection forces might drive genome adaptation using Lactobacillus (L.) casei...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28438179
DOI: 10.1186/s12864-017-3710-x
PMCID: PMC5402323

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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