A sequence polymorphism on 8q24 is associated with survival in hepatocellular carcinoma patients who received radiation therapy.

doi:10.1038/s41598-018-20700-x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A sequence polymorphism on 8q24 is associated with survival in hepatocellular carcinoma patients who received radiation therapy.

Scientific reports - 2 Feb 2018

Zhao Xiao-Mei, Xiang Zuo-Lin, Chen Yi-Xing, Yang Ping, Hu Yong, Zeng Zhao-Chong

Abstract excerpt

There is a growing consensus that genetic variation in candidate genes can influence cancer progression and treatment effects. In this study, we genotyped the rs9642880 G > T polymorphism using DNA isolated from blood samples of 271 hepatocellular carcinoma (HCC) patients who received radiotherapy treatment. We found that patients who carried the GT or TT genotypes had significantly shorter median survival times...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Hepatocellular

Share to Liver Neoplasms

Share to Polymorphism, Genetic

Share to Radiotherapy

Share to Survival

Share to Survival Analysis

Share to Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 29396413
DOI: 10.1038/s41598-018-20700-x
PMCID: PMC5797243

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A sequence polymorphism on 8q24 is associated with survival in hepatocellular carcinoma patients who received radiation therapy.PMID 29396413Read ↗

Radiogenomics: the search for genetic predictors of radiotherapy response.Semantic proximity Read ↗

Single nucleotide polymorphisms of DNA repair genes as predictors of radioresponse.Semantic proximity Read ↗

The impact of pharmacogenetics on radiation therapy outcome in cancer patients. A focus on DNA damage response genes.Semantic proximity Read ↗

Validation of genetic sequence variants as prognostic factors in early-stage head and neck squamous cell cancer survival.Semantic proximity Read ↗

Replication study for reported SNP associations with breast cancer survival.Semantic proximity Read ↗

HSPB1 gene polymorphisms predict risk of mortality for US patients after radio(chemo)therapy for non-small cell lung cancer.Semantic proximity Read ↗

Genetic variation in radiation and platinum pathways predicts severe acute radiation toxicity in patients with esophageal adenocarcinoma treated with cisplatin-based preoperative radiochemotherapy: results from the Eastern Cooperative Oncology Group.Semantic proximity Read ↗

Combinations of single nucleotide polymorphisms WWOX-rs13338697, GALNT14-rs9679162 and rs6025211 effectively stratify outcomes of chemotherapy in advanced hepatocellular carcinoma.Semantic proximity Read ↗

Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer.Semantic proximity Read ↗

Genetic variations in radiation and chemotherapy drug action pathways and survival in locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy.Semantic proximity Read ↗

XRCC1 Polymorphism Associated With Late Toxicity After Radiation Therapy in Breast Cancer Patients.Semantic proximity Read ↗

ERCC2 polymorphisms and radiation-induced adverse effects on normal tissue: systematic review with meta-analysis and trial sequential analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.