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Article

Genetic variations in radiation and chemotherapy drug action pathways and survival in locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy.

PloS one - 1 Jan 2013

Liu Huai, Qi Bin, Guo Xiang, Tang Lin-Quan, Chen Qiu-Yan, Zhang Lu, Guo Ling, Luo Dong-Hua, Huang Pei-Yu, Mo Hao-Yuan, Xiang Yan-Qun, Qiu Fang, Sun Rui, Zhang Ying, Chen Ming-Yuan, Hua Yi-Jun, Lv Xing, Wang Lin, Zhao Chong, Cao Ka-Jia, Qian Chao-Nan, Hong Ming-Huang, Mai Hai-Qiang

Abstract excerpt

BACKGROUND AND PURPOSE: Treatment outcomes vary greatly in patients with nasopharyngeal carcinoma (NPC). The purpose of this study is to evaluate the influence of radiation and chemotherapy drug action pathway gene polymorphisms on the survival of patients with locoregionally advanced NPC treated with cisplatin- and fluorouracil-based chemoradiotherapy. MATERIAL AND METHODS: Four hundred twenty-one consecutive...

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Source

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Identifiers

PMID: 24340057
DOI: 10.1371/journal.pone.0082750
PMCID: PMC3858314

Genes

MPO
ABCB1
ERCC1
MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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