Article
Single nucleotide polymorphisms of DNA repair genes as predictors of radioresponse.
Seminars in radiation oncology - 1 Oct 2010
Parliament Matthew B, Murray David
Abstract excerpt
Radiation therapy is a key modality in the treatment of cancer. Substantial progress has been made in unraveling the molecular events which underpin the responses of malignant and surrounding normal tissues to ionizing radiation. An understanding of the genes involved in processes such as DNA double-strand break repair, DNA damage response, cell-cycle control, apoptosis, cellular antioxidant defenses, and...
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