Combinations of single nucleotide polymorphisms WWOX-rs13338697, GALNT14-rs9679162 and rs6025211 effectively stratify outcomes of chemotherapy in advanced hepatocellular carcinoma.

doi:10.1111/ajco.12745

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Article

Combinations of single nucleotide polymorphisms WWOX-rs13338697, GALNT14-rs9679162 and rs6025211 effectively stratify outcomes of chemotherapy in advanced hepatocellular carcinoma.

Asia-Pacific journal of clinical oncology - 1 Apr 2018

Lin Wey-Ran, Hsu Chao-Wei, Yeh Christopher Sung-Huan, Chen Yi-Cheng, Chang Ming-Ling, Liang Kung-Hao, Lin Chen-Chun, Chu Yu-De, Yeh Chau-Ting

Abstract excerpt

AIM: A genome-wide association study (GWAS) had identified a single nucleotide polymorphism (SNP), GALNT14-rs9679162, capable of predicting chemotherapy responses in advanced hepatocellular carcinoma (HCC). Here, we revisited the GWAS database to search for necessary SNPs that could improve our outcome prediction. METHODS: A cohort of 116 HCC patients receiving split-dose chemotherapy composed of 5-fluorouracil,...

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PMID: 28695683
DOI: 10.1111/ajco.12745

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GALNT14
WWOX

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