HSPB1 gene polymorphisms predict risk of mortality for US patients after radio(chemo)therapy for non-small cell lung cancer.

doi:10.1016/j.ijrobp.2012.03.032

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Article

HSPB1 gene polymorphisms predict risk of mortality for US patients after radio(chemo)therapy for non-small cell lung cancer.

International journal of radiation oncology, biology, physics - 1 Oct 2012

Xu Ting, Wei Qingyi, Lopez Guerra Jose Luis, Wang Li-E, Liu Zhensheng, Gomez Daniel, O'Reilly Michael, Lin Steven Hsesheng, Zhuang Yan, Levy Lawrence B, Mohan Radhe, Zhou Honghao, Liao Zhongxing

Abstract excerpt

PURPOSE: We investigated potential associations between single-nucleotide polymorphisms (SNPs) in the heat shock protein beta-1 (HSPB1) gene and overall survival in US patients with non-small cell lung cancer (NSCLC). METHODS AND MATERIALS: Using available genomic DNA samples from 224 patients with NSCLC treated with definitive radio(chemo)therapy, we genotyped 2 SNPs of HSPB1 (NCBI SNP nos. rs2868370 and...

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Identifiers

PMID: 22608953
DOI: 10.1016/j.ijrobp.2012.03.032
PMCID: PMC3426644

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HSPB1

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